Explain how glomerular hydrostatic pressure (GHP) and glomerular colloid osmotic pressure (GCOP) act as opposing forces during glomerular filtration

What will be an ideal response?


Glomerular hydrostatic pressure (GHP) is largely determined by systemic blood pressure. Hydrostatic pressure is the force of fluid exerts against the wall of a container (such as a blood vessel). Blood trying to exit the glomerulus via the efferent arteriole is backed up into the glomerulus. Blood is pushed against the walls of the capillaries, favoring filtration. Glomerular colloid osmotic pressure (GCOP) is the pressure created by proteins such as albumin in the plasma. The GCOP opposes filtration by pulling fluids back into the glomerular capillaries.

Anatomy & Physiology

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