A client admitted to the emergency department for vaginal bleeding is surprised to find she is in the third trimester of pregnancy
An ultrasound determines the fetus is not viable. The nurse recognizes that which drug could be responsible for the fetal demise?
1. Selective serotonin reuptake inhibitors (SSRIs)
2. Fluoroquinolone
3. Acetaminophen
4. Nonsteroidal anti-inflammatory drugs (NSAIDs)
5. Angio-converting enzyme inhibitor (ACE inhibitor)
Correct Answer: 4,5
Rationale 1: SSRI drugs are category C and do not cause fetal demise.
Rationale 2: Fluoroquinolone is category C and does not cause fetal demise.
Rationale 3: Acetaminophen is category B and does not cause fetal demise.
Rationale 4: Nonsteroidal anti-inflammatory drugs (NSAIDs) can cause fetal demise in the third trimester.
Rationale 5: ACE inhibitors are category D and can cause fetal demise.
Global Rationale: Nonsteroidal anti-inflammatory drugs (NSAIDs) can cause fetal demise in the third trimester. ACE inhibitors are category D and can cause fetal demise. SSRI drugs and fluoroquinolones are category C and do not cause fetal demise. Acetaminophen is category B and does not cause fetal demise.
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