Explain the cellular events required for the production of protective IgG antibodies against bacterial polysaccharide components and the development of memory
What will be an ideal response?
First, dendritic cells process the toxoid epitope and activate CD4 T cells, which differentiate into TFH cells. Then naive B cells bearing IgM antibodies specific for the polysaccharide take up the conjugate by receptor-mediated endocytosis. The toxoid epitopes are subsequently presented with MHC class II molecules on the B-cell surface to activated toxoid-specific CD4 TFH. The resulting T cell–B cell cognate interaction provides everything needed for an efficient immune response generating high-affinity, polysaccharide-specific protective IgG antibodies and the establishment of both T-cell memory and B-cell memory.
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Break down the medical word into its word parts, and give the meaning of each word part. Then, give the definition of the medical word.
Epiglottitis Definition: Prefix and definition: Combining form and definition: Suffix and definition: ?
In bacterial endocarditis, the mass of bacteria that forms is referred to as:
A) bacterioma. B) a thrombus. C) pyoma. D) vegetation.
Which of the following is associated with antagonistic autoantibodies against cell-surface receptors or adhesion molecules? (Select all that apply.)
a. myasthenia gravis b. rheumatoid arthritis c. insulin-resistant diabetes d. Graves' disease e. pemphigus vulgaris.
Which of the following types of fiber is associated with lowering cholesterol?
A) Soluble B) Insoluble C) Complex D) Digestible