A 78-year-old woman, who lives alone and is forgetful, is being seen by her home health nurse. In reviewing the patient's medication, the nurse discovers that the patient is taking Azithromycin (Zithromax) for urethritis
Why would this be a good choice of antibiotics for this patient? A) The half-life of the drug is 3 to 7 hours.
B) It is taken only once a day.
C) It has very few adverse effects.
D) It can be given without consideration to drug–drug interactions.
B
Feedback:
Given that the patient is "forgetful" and lives alone, a daily dose would likely promote improved compliance. Azithromycin can be administered once daily because the half-life is 68 hours. Azithromycin is associated with GI adverse effects and can cause pseudomembranous colitis; neurological symptoms can occur as well. Azithromycin (Zithromax) may adversely interact with cardiac glycosides, oral anticoagulants, theophyllines, carbamazepine, and corticosteroids to name a few agents.
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