The nurse practitioner is debating whether to prescribe darbepoetin alfa (ARAN esp) or epoetin alfa. The nurse practitioner decides to write the order for darbepoetin alfa (ARAM esp), because it has the advantage over erythropoietin that it
a. is less painful to inject.
b. can be administered less frequently.
c. has a shorter half-life.
d. is less likely to exacerbate hypertension.
B
Darbepoetin alfa is cleared more slowly than epoetin alfa and has a longer half-life. It therefore can be administered less often and is more convenient.
Darbepoetin alfa is not less painful to inject and is not less likely to exacerbate hypertension.
Darbepoetin alfa has a longer half life than epoetin alfa.
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