The nurse can explain the therapeutic action of monoamine oxidase (MAO) inhibitors as blocking
neurotransmitter reuptake, causing
a. increased concentration of neurotransmitter in the synaptic gap.
b. decreased concentration of neurotransmitter in the synaptic gap.
c. destruction of receptor sites.
d. limbic system stimulation.
ANS: A
If the reuptake of a substance is inhibited, it accumulates in the synaptic gap and its concentration
increases, permitting ease of transmission of impulses across the synaptic gap. Normal transmission
of impulses across synaptic gaps is consistent with normal rather than depressed mood. The other
options are not associated with blocking neurotransmitter reuptake.
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