The nurse is caring for a client with a suspected autoimmune disorder. What concept related to the client's condition does the nurse recognize is true? Select all that apply.

A) It is necessary to determine that immunologic findings do not have another cause.
B) Diagnosis is currently based on serologic testing and clinical findings.
C) Each method of serologic testing involves either concentrating or diluting the client's serum.
D) Genetic testing is considered the most reliable way to diagnose autoimmune disorders.
E) Serologic testing reveals autoantibodies directed against cellular components.


A) It is necessary to determine that immunologic findings do not have another cause.
B) Diagnosis is currently based on serologic testing and clinical findings.
E) Serologic testing reveals autoantibodies directed against cellular components.

Explanation: A) In order to diagnose an autoimmune disorder, it is necessary to determine that immunologic findings do not have another cause.
B) In order to diagnose an autoimmune disorder, it is necessary to determine that immunologic findings do not have another cause. Diagnosis is currently based on serologic testing and clinical findings.
C) The serologic testing for autoimmune diseases involves diluting the body's serum until it no longer produces a reaction to antigen-coated material.
D) Although genetic testing for autoimmune disorders may be available in the future, there is currently no genetic testing available for the diagnosis of autoimmune disorders.
E) Serologic testing reveals autoantibodies directed against cellular components. This means that the testing shows these autoantibodies present in the client, where otherwise they would not be present.

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