Through genetic testing, a patient learns that he has an apolipoprotein E2 gene. What should this information suggest to the nurse?

Question

1. The patient is at reduced risk for developing Alzheimer disease.
2. The patient is at increased risk for developing Alzheimer disease.
3. The patient is at risk for contracting malaria.
4. The patient is at risk for developing colorectal cancer.

Answer 1

Correct Answer: 1

The apolipoprotein E gene provides instructions to make a protein that combines with fats in the body to form molecules called lipoproteins which are responsible for packaging cholesterol and other fats and carrying them through the bloodstream. Research has shown that a person who inherits at least one E4 allele will have a greater chance of developing Alzheimer disease. Inheriting the E2 allele does not indicate that a person is more likely to develop Alzheimer disease. The apolipoprotein E gene is not a predictor for contracting malaria or developing colorectal cancer.