Define the definition of toxicity and explain the relationship it has with acute toxicity, effective dose, and the dose – response curve
What will be an ideal response?
Answer: Any substance, no matter how benign, has the potential for toxicity if the dose—the amount in which the substance is taken—is high enough. The question of a drug's safety, or its relative safety when compared to other drugs, centers on the possibility that it may be toxic at relatively low doses.
Toxicity is the physical or psychological harm that a drug might present to the user. When there is a possibility that the short-term effects of a particular drug will trigger a toxic reaction, then this drug is identified as having some level of acute toxicity. Acute toxicity is the physical or psychological harm a drug might present to the user immediately or soon after the drug is ingested into the body.
The dose-response curve is the increasing probability of a certain drug effect as the dose level rises. The effective dose is the minimal dose of a particular drug necessary to produce the intended drug effect in a given percentage of the population.
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