The sequence Lys-Asp-Glu-Leu (KDEL) serves to retain proteins in the ER by

a. preventing their packaging into vesicles destined for the Golgi.
b. binding to receptors within the membranes of the ER and Golgi, which retain them or return them to the ER.
c. binding the SRP receptor in the ER membrane.
d. associating with the lipids in the ER membrane.


Ans: b. binding to receptors within the membranes of the ER and Golgi, which retain them or return them to the ER.

Biology & Microbiology

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Biology & Microbiology