A nurse would question a prescription for sulfasalazine (Azulfidine) if the client is also taking which medication?

1. Insulin
2. Digoxin
3. Warfarin
4. Penicillin
5. Vitamin C


1,2,3
Rationale 1: Clients with diabetes may experience hypoglycemia if sulfasalazine is taken concurrently.
Rationale 2: Absorption of digoxin may be decreased.
Rationale 3: Anticoagulation effects may be increased.
Rationale 4: There is no drug–drug interaction with penicillin.
Rationale 5: There is no drug–drug interaction with vitamin C.
Global Rationale: Clients with diabetes may experience hypoglycemia if sulfasalazine is taken concurrently. Absorption of digoxin may be decreased. Anticoagulation effects may be increased. There is no drug–drug interaction with penicillin. There is no drug–drug interaction with vitamin C.

Nursing

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