Are the statements below true or false? Explain your answer
A. Statement 1: Generally, in a given organism, the S, G2, and M phases of the cell cycle take a defined and stereotyped amount of time in most cells.
B. Statement 2: Therefore, the cell-cycle control system operates primarily by a timing mechanism, in which the entry into one phase starts a timer set for sufficient time to complete the required tasks. After a given amount of time has elapsed, a molecular "alarm" triggers movement to the next phase.
A. True. In nearly all cells in an organism, the S, G2, and M phases of the cell cycle take the same amount of time. The different timing of cell division in different cell types is due to variable lengths of the G1 phase or to withdrawal into the G0 state.
B. False. The cell-cycle control system does use a timing mechanism of sorts, but it also employs various surveillance and feedback mechanisms (checkpoints). Cells will not embark on later events or phases until the earlier events or phases have been completed successfully. In response to a defect or a delay in a cell-cycle event, cells engage molecular brakes to arrest the progression of the cell cycle at various checkpoints, to allow time for completion or repair.
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