Lisa has a rare genetic defect that causes acute sun-sensitivity. Her mother has the defect, but her father does not. All of Lisa's siblings, two brothers and a sister, are also affected. All four siblings are married, but none of their spouses has the mutant gene. Draw a pedigree for this family. Identify and explain the most likely mode of transmission for this disorder
What will be an ideal response?
The most likely mode of transmission for this disorder is via maternal mitochondria. Mitochondria carry DNA molecules that encode information for 37 mitochondrial genes. Mitochondria are transmitted from mothers to all their children through the cytoplasm of the egg (sperm do not contribute cytoplasm or mitochondria at fertilization). As a result, genetic disorders caused by mutations in mitochondria are maternally inherited and produce a distinctive pattern of inheritance. All the children of affected females are affected. Affected females will transmit the disorder to all their offspring, but affected males cannot transmit the mutations to any of their children.
You might also like to view...
This phylum of vascular, seed-bearing plants includes pines, spruces, firs, hemlocks, junipers,
cypresses, and redwoods. Most of them are evergreens that form woody reproductive cones.
a. Cycadophyta b. Anthophyta c. Gnetophyta d. Coniferophyta e. Ginkgophyta
_____ is(are) formed during the oxidation of pyruvate to acetyl CoA
1.Glucose 2.CO2 3.NADH+ 4.ATP 5.Both NADH+ and CO2
Which system collects and returns tissue fluid to the blood?
a. immune system. b. skeletal system. c. integumentary system. d. endocrine system. e. lymphatic system.
Lithotrophy: Inorganic e- Donors
What will be an ideal response?