The nursing instructor is discussing drug therapy in the older adult. What would the instructor tell the students about what could affect therapeutic dosing in an older adult?
A) Changes in the gastrointestinal (GI) system can reduce drug absorption.
B) In older adults, drugs enter into circulation more quickly.
C) In older adults, drugs are distributed to a smaller portion of the tissues.
D) In older adults, drugs have an increased action.
A
Feedback:
As patients age, the body undergoes many normal changes that can affect drug therapy, such as a decreased blood volume, decreased GI absorption, reduced blood flow to muscles or skin, and changes in receptor site responsiveness. They are not released more quickly into circulation; distributed to a smaller portion of tissue; nor do they have an increased action.
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