While explaining the role of skeletal muscle relaxants, such as succinylcholine, used during anesthesia, the faculty mentions that these effects are caused by blocking:
A) Nicotinic acetylcholine receptors, muscle-type receptor (NM)
B) Norepinephrine
C) Muscarinic acetylcholine receptors
D) N2, neuronal-type receptor, a type of nicotinic acetylcholine receptor
Ans: A
Feedback:
Some skeletal muscle relaxants, such as succinylcholine, can be used to induce muscle relaxation and short-term paralysis in anesthesia by blocking NM receptors at the neuromuscular junction. The drug atropine is a competitive antagonist for the muscarinic acetylcholine receptor that prevents the action of acetylcholine at excitatory and inhibitory muscarinic receptor sites. Norepinephrine is released at most sympathetic nerve endings.
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