The "one gene–one enzyme" hypothesis of George Beadle and Edward Tatum was an oversimplification because:

A. mutations may not completely inactivate an enzyme.
B. some enzymes contain more than one polypeptide.
C. some enzymes can be phosphorylated.
D. auxotrophs can be corrected.
E. some RNAs are independently catalytic.


B

Biology & Microbiology

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