The nurse is providing discharge instructions to a patient about drug-drug and drug-food interactions. Which of the following statements by the patient indicates a lack of understanding about these medications?
a. "I can take my cefotetan (Cefotan) with my warfarin (Coumadin)."
b. "I can take ceftriaxone (Rocephin) and spironolactone (Aldactone)."
c. "I can take yogurt with active cultures to counteract my vulvocandidiasis."
d. "I can drink soda to enhance the effects of my fluconazole (Diflucan)."
ANS: A
Cephalosporins disrupt prothrombin levels by interfering with vitamin K metabolism, and patients taking other anticoagulant medications (eg, warfarin) are especially at risk. This statement indicates a need for further teaching.
Ceftriaxone can be taken with spironolactone; no further teaching is needed.
Yogurt with active cultures has been shown to help eliminate yeast infections in women; no further teaching is needed.
Soda has been shown to enhance the effects of fluconazole; no further teaching is needed.
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