What is the difference between MHC variation due to multigene families and that due to allelic polymorphism?

What will be an ideal response?


Multigene family refers to the presence of multiple genes for MHC class I and MHC class II molecules in the genome, encoding a set of structurally similar proteins with similar functions. MHC polymorphism is the presence of multiple alleles (in some cases several hundreds) for most of the MHC class I and class II genes in the human population.

Health & Biomechanics

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