A patient receiving chemotherapy and prescribed ondansetron (Zofran) asks the nurse why the drug is given before meals. What is the nurse's best response?
a. "Ondansetron is given 30 minutes before your meals to prevent nausea."
b. "The purpose of this drug is to move food rapidly through your GI tract."
c. "This drug works by preventing nausea caused by morphine given for your pain."
d. "If this drug were given after your meals, the food would interfere with its ab-sorption."
A
Ondansetron is an antinausea drug that is given 30 minutes before meals and at bedtime to pre-vent the nausea that is associated with chemotherapy. Metoclopramide (Reglan) increases peris-talsis to help move food through the GI tract. Antihistamines prevent the nausea and vomiting caused by opiate drugs such as morphine. If the drug were given after meals, its purpose would not be met.
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