If hepatic and renal functions are decreased, the half-life of a drug is prolonged, which may result in:
A. potentiation
B. increased sedative effects
C. drug toxicity
D. drug ineffectiveness
c
Rationale: If the efficiency of the hepatic and renal systems is decreased, the half-life of the drug is prolonged, resulting in drug toxicity. There are special medications that must be administered in reduced dosages in elderly patients.
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