Explain how HATs and HDACs can lead to the formation of cancer
What will be an ideal response?
HATs usually lead to gene expression, and HDACs usually lead to gene repression. In cancer cells if HATs are mutated, then genes that are normally expressed to prevent cancer are now repressed, which can lead to cancer. In addition, in cancer cells if HDACs are mutated, then genes that are normally inactive to suppress cancer will now be expressed leading to cancer.
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A single, simple, recessively inherited mutation inactivates the enzyme that converts phenylalanine to tyrosine. Homozygous recessive individuals possess an excessive amount of phenylalanine and a deficiency of tyrosine. Additionally, these individuals may be mentally deficient, have abnormally light hair and abnormally light skin color. This disorder is an example of
A. incomplete penetrance. B. incomplete dominance. C. pleiotropy. D. polygenic inheritance.
Which of the following statements about the nucleus is not true?
A. The nucleus usually contains a nucleolus region which is where ribosome assembly begins B. The nucleus is the site of protein assembly C. The nucleus stores the coded instructions for making the cell's proteins D. The nucleus is surrounded by a nuclear envelope that lets materials in and out
Which of the following bacteria play a role in abortion in cattle and sheep?
A. Campylobacter fetus subsp. venerealis B. Campylobacter fetus subsp. fetus C. Campylobacter rectus D. Campylobacter concisus
While focusing on a microscope on high power, a student crushed the coverslip. The student probably
a. shut the light off b. turned up the light intensity c. rotated the eyepiece d. used the coarse adjustment