Which of the following assists in the diagnosis of myasthenia gravis?
A. Tensilon test
B. Tinel sign
C. McGill questionnaire
D. ACTH challenge test
ANS: A
A highly sensitive test for the diagnosis of myasthenia gravis is the measurement of serum levels of circulating acetylcholine receptor antibodies. The Tensilon test is definitive and involves blocking acetylcholine by administering edrophonium chloride. If the patient has myasthenia, the symtpoms will temproarily worsen after the administration of edrophonium chloride. Since thymomas also can be present in these patients, a computed tomography (CT) scan of the chest should be performed.
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