Some of the enzymes that oxidize sugars to yield usable cellular energy (for example, ATP) are regulated by phosphorylation
For these enzymes, would you expect the inactive form to be the phosphorylated form or the dephosphorylated form? Explain your answer.
In general, the inactive form is the phosphorylated form. The main purpose of glycolysis and the citric acid cycle is to generate ATP; thus, the enzymes are inactive when the concentration of ATP is high and active when it is low. It makes sense that cells would not want to have to phosphorylate their enzymes to turn them on when ATP levels are already low, because phosphorylation requires ATP.
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