What is the rationale for administering fibrinolytic agents, such as streptokinase, within hours of the onset of myocardial infarction?
a. Enhances myocardial oxygenation
b. Lyses the blood clot
c. Promotes platelet aggregation
d. Inhibits clotting mechanisms
ANS: B
Fibrinolytic agents such as streptokinase dissolve or lyse recently formed thrombi. The goals of thrombolytic therapy are to lyse the thrombus during the early stages of clot formation, restore circulation to the areas distal to the thrombus, and reduce morbidity after thromboembolism formation. Fibrinolytic agents do not have an effect on myocardial oxygenation and do not promote platelet aggregation or inhibit clotting mechanisms.
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