The client receives esomeprazole (Nexium). He asks the nurse why that medication is better than his cimetidine (Tagamet). What is the best response by the nurse?
1. "It is about the same but a lot cheaper than your cimetidine (Tagamet)."
2. "It decreases acid in your stomach better than cimetidine (Tagamet)."
3. "It is about the same but has fewer side effects than your cimetidine (Tagamet)."
4. "It is not as effective as cimetidine (Tagamet) but kills bacteria better."
2
Rationale 1: Esomeprazole (Nexium) is not cheaper than cimetidine (Tagamet).
Rationale 2: Proton-pump inhibitors reduce acid secretion to a greater extent than H2-receptor antagonists, and have a longer duration of action.
Rationale 3: Esomeprazole (Nexium) does not have fewer side effects than cimetidine (Tagamet).
Rationale 4: Esomeprazole (Nexium) is more effective than cimetidine (Tagamet) but will not kill bacteria.
Global Rationale: Proton-pump inhibitors reduce acid secretion to a greater extent than H2-receptor antagonists and have a longer duration of action. Esomeprazole (Nexium) is not cheaper than or have fewer side effects than cimetidine (Tagamet). Esomeprazole (Nexium) is more effective than cimetidine (Tagamet) but will not kill bacteria.
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