A client admitted with persistent asthma has a history of hypertension. Which class of asthma drugs must be used cautiously with clients who have hypertension?
1. Inhaled corticosteroids
2. Oral short-acting beta-adrenergic agonists
3. Inhaled anticholinergic medications
4. Mast cell stabilizers
Correct Answer: 2
Rationale 1: Inhaled corticosteroids decrease inflammation and do not affect the sympathetic nervous system.
Rationale 2: Oral beta-adrenergic agonists activate the sympathetic nervous system and must be used cautiously in clients with hypertension.
Rationale 3: Inhaled anticholinergic drugs have few systemic side effects; hypertension is not one of them.
Rationale 4: Mast cell stabilizers decrease inflammation. They are safe for use in clients with hypertension.
Global Rationale: Because albuterol may exhibit cardiovascular effects in some patients, caution is required when administering these agents to persons with a history of tachyarrhythmias, prolongation of the QT interval, coronary artery disease, or hypertension (HTN). Inhaled corticosteroids decrease inflammation and do not affect the sympathetic nervous system. Inhaled anticholinergic drugs have few systemic side effects; hypertension is not one of them. Mast cell stabilizers decrease inflammation. They are safe for use in clients with hypertension.
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