A client is brought to the emergency department (ED) after overdosing on acetaminophen last night. The client is conscious and tearful. The nurse prepares to administer the antidote to acetaminophen:
Standard Text: Select all that apply.
1. in three stages by intravenous administration.
2. rectally by suppository.
3. orally.
4. intramuscularly.
5. subcutaneously.
Correct Answer: 1,3
Rationale 1: Acetylcysteine is administered in the "three-bag" method.
Rationale 2: Acetylcysteine is not administered rectally.
Rationale 3: Acetylcysteine can be administered orally.
Rationale 4: Acetylcysteine is not administered intramuscularly.
Rationale 5: Acetylcysteine is not administered subcutaneously.
Global Rationale: Acetaminophen overdose is treated with oral or IV acetylcysteine (Acetadote). For maximum effectiveness, the antidote should be administered within 8 hours of acetaminophen ingestion. The IV form (Acetadote) is administered by the "three-bag method".
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