Because they cause vasoconstriction, alpha1-adrenergic agonists are especially useful for:
a. extending the duration of local anesthetics.
b. producing mydriasis to facilitate ophthalmic examinations.
c. slowing the heart rate in tachycardic patients.
d. treating hypotension.
ANS: A
The vasoconstrictive effects of alpha1-adrenergic agonists, such as epinephrine, help delay absorption of a local anesthetic, prolonging the anesthetic's effects. These agents can increase blood pressure but are not the primary drugs used except in emergency situations. Alpha1 receptors in the radial muscles of the iris, not vasoconstriction, cause mydriasis. Reflex bradycardia is a side effect and not a clinical use of these agents.
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