Which of the following is evidence supporting the Lyon hypothesis of X inactivation?
A. A highly condensed structure is consistently observed in female cells, but not in normal male cells.
B. Female mammals that are heterozygous for X-linked traits are phenotypic mosaics.
C. A female cat that is homozygous for coat color cannot have a calico phenotype.
D. Calico patterns of coat color are never exactly the same.
E. All of the answers are correct.
Answer: E
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