Which of the following best describes the effects of somatostatin?
a. It stimulates the release of antidiuretic hormone and oxytocin.
b. It suppresses the release of pancreatic polypeptide.
c. It inhibits the release of insulin and glucagon.
d. It inhibits the release of thyroid-stimulating hormone and thyroid hormone.
C
Somatostatin decreases glucagon secretion, and in high quantities, it decreases insulin release. Hyperglycemia stimulates the activity of the delta cells. It is theorized that the release of insulin enables somatostatin to control beta-cell activity. Somatostatin may be involved in the regulation of the postprandial influx of glucose into cells.
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