Considering potential harmful side effects, which system would the nurse address as a priority area of assessment when a client is given lamivudine (Epivir)?
1. Cardiac
2. Renal
3. Hepatic
4. Pulmonary
Correct Answer: 3
Rationale 1: Although important, cardiac assessment is not as important an area of assessment as another area.
Rationale 2: Although important, renal assessment is not as important an area of assessment as another area.
Rationale 3: Lamivudine can cause an unusual type of liver abnormality called lactic acidosis and hepatomegaly with steatosis. This can result in death.
Rationale 4: Although important, pulmonary assessment is not as important an area of assessment as another area.
Global Rationale: Lamivudine can cause an unusual type of liver abnormality called lactic acidosis and hepatomegaly with steatosis. This can result in death. The remaining assessments are important, but are not the highest priority.
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