A 69-year-old woman has been taking metformin for the treatment of type 2 diabetes for several years. Which of the following changes in the woman's laboratory values may demonstrate a need to discontinue the medication?
A) A decrease in hemoglobin and hematocrit
B) A decrease in glomerular filtration rate
C) A decrease in potassium accompanied by an increase in sodium
D) An increase in white blood cells
B
Feedback:
It is essential to discontinue metformin if renal impairment occurs. The other listed changes in laboratory values do not necessarily indicate that metformin should be discontinued.
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