Which of the following neuroimaging diagnostic evaluations is highly predictive of dementia of Alzheimer's type?
A) Neurohistologic lesion in basal ganglia
B) Small infarctions in the white matter of brain
C) Bilateral temporal and parietal perfusion defects
D) Infarction of small- and medium-sized cerebral vessels
Ans: C
The predominate finding of bilateral posterior temporal and parietal perfusion defects is thought to be highly predictive of DAT. Parkinson's disease is due to the presence of neurohistologic lesions in the basal ganglia. Binswanger's disease is a type of vascular dementia that is characterized by the presence of many small infarctions affecting the white matter of the brain. Vascular dementia is thought to result from infraction of small- and medium-sized vessels causing parenchymal lesions to occur over wide areas of the brain.
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