Which of the following categories of oral antidiabetic agents enhance insulin action at the receptor site without increasing insulin secretion from the beta cells of the pancreas?
A) Sulfonylureas
B) Biguanides
C) Thiazolidinediones
D) Alpha glucosidase inhibitors
Ans: C
Feedback: Biguanides facilitate insulin's action on peripheral receptor sites. Sulfonylureas exert their primary action by directly stimulating the pancreas to secrete insulin and therefore require a functioning pancreas to be effective. Thiazolidinediones enhance insulin action at the receptor site without increasing insulin secretion from the beta cells of the pancreas. Alpha glucosidase inhibitors work by delaying the absorption of glucose in the intestinal system, resulting in a lower postprandial blood glucose level.
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