A patient in the chronic phase of chronic myelogenous leukemia (CML) will meet which criteria?

A) Blast cells account for less than 10% of all cells in blood or bone marrow.
B) Blast cells account for 10-19% of all cells in blood or bone marrow.
C) Blast cells account for 20-49% of all cells in blood or bone marrow.
D) Blast cells account for more than 50% of all cells in blood or bone marrow.


A) Blast cells account for less than 10% of all cells in blood or bone marrow.
Explanation: A) Staging systems for CML do not exist; instead, CML is classified according to phase (chronic, accelerated, or blast), which is based on the number of blast cells present in the blood and bone marrow. In chronic phase CML, blast cells account for fewer than 10% of all cells in the blood or bone marrow. In accelerated phase CML, blast cells increase and account for 10-19% of all cells in the blood or marrow. During the blastic phase, blast cells account for over 20% of all cells in the blood or marrow.
B) Staging systems for CML do not exist; instead, CML is classified according to phase (chronic, accelerated, or blast), which is based on the number of blast cells present in the blood and bone marrow. In chronic phase CML, blast cells account for fewer than 10% of all cells in the blood or bone marrow. In accelerated phase CML, blast cells increase and account for 10-19% of all cells in the blood or marrow. During the blastic phase, blast cells account for over 20% of all cells in the blood or marrow.
C) Staging systems for CML do not exist; instead, CML is classified according to phase (chronic, accelerated, or blast), which is based on the number of blast cells present in the blood and bone marrow. In chronic phase CML, blast cells account for fewer than 10% of all cells in the blood or bone marrow. In accelerated phase CML, blast cells increase and account for 10-19% of all cells in the blood or marrow. During the blastic phase, blast cells account for over 20% of all cells in the blood or marrow.
D) Staging systems for CML do not exist; instead, CML is classified according to phase (chronic, accelerated, or blast), which is based on the number of blast cells present in the blood and bone marrow. In chronic phase CML, blast cells account for fewer than 10% of all cells in the blood or bone marrow. In accelerated phase CML, blast cells increase and account for 10-19% of all cells in the blood or marrow. During the blastic phase, blast cells account for over 20% of all cells in the blood or marrow.

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