About 10-20% of patients with Leigh Syndrome, a mitochondrial disease, have a mutation in MT-ATP6, a gene that
codes for ATP synthase. These patients often experience high levels of _____ in their cells due to an increase in levels of
pyruvate that are unable to convert to acetyl-CoA.
a. NADH
b. FADH2
c. lactate
d. ethanol
e. carbon dioxide
ANSWER: c
You might also like to view...
During sporulation in Bacillus subtilis, the response regulator that positively controls many genes needed for sporulation and negatively controls genes not needed during sporulation is
A. SpoOB. B. SpoOF. C. SpoOC. D. SpoOA.
Magnesium is not considered a growth factor for microorganisms, because growth factors are always organic compounds
Indicate whether the statement is true or false.
Which of the following best describes the tRNA binding sites of the ribosome?
A. Only one of the three sites can be occupied by a tRNA molecule at any given time. B. Each tRNA that associates with the ribosome must first bind in the P site and then move to the A site. C. The P site contains the tRNA molecule covalently bound to the growing chain of amino acids. D. All tRNAs leave the ribosome through the A site.
Matching II. Choose the one most appropriate
answer for each. 1. ___ control over enzyme activity 2. ___ transcript processing 3. ___ post-translational control 4. ___ transcriptional control 5. ___ transport control A. influences the amount and kinds of mRNA assembled from structural genes B. snipping out of transcript regions; chemical modification of transcript before it arrives at ribosome control C. nuclear envelope selectively regulates passage of transcripts D. phosphorylation of translated protein E. for example, the interior environmental pH determines whether a protein can act as a cell catalyst