Of the following group of individuals, which one has the least risk for development of restrictive lung disease?
1. 75-year-old male with alpha-antitrypsin (AAT) deficiency
2. 70-year-old female with severe kyphoscoliosis
3. 56-year-old morbidly obese male
4. 40-year-old female with newly diagnosed sarcoidosis
75-year-old male with alpha-antitrypsin (AAT) deficiency
Rationale: Alpha-antitrypsin (AAT) deficiency is a genetic risk factor associated with chronic obstructive lung disease. Restrictive lung disorders may occur in kyphoscoliosis, the morbidly obese, and sarcoidosis.
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