Which of the following precipitates 80% of the cases of aplastic crisis?
a. pneumococcal infection c. staphylococcus
b. human parvovirus B-19 d. streptococcus
B
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A Incorrect. Pneumococcal infection does not precipitate 80% of the cases of aplastic crisis.
B Correct. Aplastic crisis occurs when there is a decrease in erythropoiesis, despite the shortened life span of sickled RBCs and the body's need for increased RBC production. In 80% of cases, this type of crisis is precipitated by an infection with human parvovirus B-19 . The infection is self-limited, but highly contagious and warrants isolation from persons vulnerable to infection. Aplastic crisis results in severe anemia.
C Incorrect. Staphylococcus does not precipitate 80% of the cases of aplastic crisis.
D Incorrect. Streptococcus does not precipitate 80% of the cases of aplastic crisis.
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