The health care provider is prescribing drug therapy for a patient who is 10 weeks pregnant. In prescribing the drug, the health care provider must take into consideration that an expected out-come for this patient at this stage of her pregnancy is:
a. Increased peripheral vascular resistance
b. Increased cardiac output
c. Increased gastric acid secretion
d. Decreased renal blood flow and glomerular filtration rate (GFR)
ANS: B
Cardiac output rises in early pregnancy as a result of the increasing heart rate. Later in pregnancy, stroke volume rises by 40 mL above nonpregnant levels, reaching a peak at 20 to 24 weeks of gestation. Distribution of blood flow also changes as cardiac output increases. The most dramatic increase occurs in uterine blood flow, with a change from 50 mL/min to 500 to 700 mL/min. This increase represents 10% to 20% of the cardiac output.
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