An older adult is currently prescribed both aspirin (81 mg) and ibuprofen daily. What instructions are most important for the nurse to provide to assure the expected outcomes for this client?
a. The medications should be taken together to ensure the effectiveness of both medications
b. Take ibuprofen 30 minutes after the aspirin so as to not interfere with its effectiveness
c. The aspirin will negatively affect the analgesic affect of the ibuprofen
d. The medications should be taken at least 4 hours apart to minimize risk of gastric irritation
ANS: B
In 2006 the Food and Drug Administration in the United States issued a warning regarding the concomitant use of aspirin (81 mg) and ibuprofen. When taken together the aspirin is less cardio-protective; that is, there is less anti-platelet effect increasing the person's risk for a cardiac event. Persons who take immediate release aspirin and take a single dose of ibuprofen 400mg: It should be at least 30 minutes after or 8 hours before the aspirin.
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