Using radiolabeled amino acids, Palade and colleagues were able to define the pathway taken by secreted proteins. Which of the following represents that pathway?
a. Rough ER ? smooth ER ? Golgi ? secretory vesicles ? cell exterior
b. Rough ER ? smooth ER ? Golgi ? endosomes ? cell exterior
c. Rough ER ? Golgi ? lysosomes ? cell exterior
d. Rough ER ? Golgi ? secretory vesicles ? cell exterior
Ans: d. Rough ER ? Golgi ? secretory vesicles ? cell exterior
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