Steve decides to make a meal for some of his friends. He uses a variety of foods to prepare the meal, including some canned mushrooms. Unfortunately, he gives his friends a mild case of botulism food poisoning. His friends report blurred vision and

trouble speaking due to a flaccid paralysis of the muscle cells by the botulinum toxin. Propose a mechanism by which this toxin would inhibit muscle contraction.

What will be an ideal response?


If the muscles become flaccid, they cannot be stimulated to contract. The most likely cause would be that the toxin is somehow interfering with the action of acetylcholine. The toxin may be blocking acetylcholine release, or it may be blocking the binding of acetylcholine to the receptors on the muscle.

Biology & Microbiology

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