A patient who has type 2 diabetes will begin taking glipizide [Glucotrol]. Which statement by the patient is concerning to the nurse?
a. "I will begin by taking this once daily with breakfast."
b. "It is safe to drink grapefruit juice while taking this drug."
c. "I may continue to have a glass of wine with dinner."
d. "I will need to check my blood sugar once daily or more."
C
Glipizide is a sulfonylurea antidiabetic agent and can cause a disulfiram-like reaction when com-bined with alcohol. Patients should be taught to avoid alcohol while taking this medication. The initial dosing is once daily with breakfast. There is no drug interaction with grapefruit juice. Pa-tients will need to monitor their blood glucose.
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