A client with nausea and vomiting is to receive an antiemetic that inhibits the vomiting center in the brain. Which of the following would the nurse expect the physician to order most likely?
A) Ondansetron (Zofran)
B) Hydroxyzine (Vistaril)
C) Prochlorperazine (Compazine)
D) Promethazine (Phenergan)
C
Feedback:
Prochlorperazine is a phenothiazine that inhibits the chemoreceptor trigger zone (CTZ) and the vomiting center in the brain. Ondansetron blocks receptors for 5 HT3, affecting the neural pathways involved in nausea and vomiting. Hydroxyzine and promethazine are antihistamines that block H1 receptors, resulting in a decrease in stimulation of the CTZ and vomiting.
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