The leading causes of death in the United States are due to:
A. Multifactorial inheritance
B. Single gene mutations
C. X-linked disorders
D. Aneuploidy
ANS: A
Most disease-causing conditions are not due to a single-gene disorder but are due to multifactorial inheritance, a result of genomics and environmental or behavioral influences. In fact, the leading causes of mortality in the United States—heart disease, cerebrovascular disease, diabetes, and cancer—are all multifactorial. Most congenital malformation, hypertension, arthritis, asthma, obesity, epilepsy, Alzheimer's, and mental health disorders are also multifactorial.
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