A child has been admitted to the hospital unit with a diagnosis of minimal-change nephrotic syndrome (MCNS). The clinical manifestations will include which of the following?
1. Hematuria,bacteriuria,weight gain
2. Gross hematuria,albuminuria,fever
3. Massive proteinuria,hypoalbuminemia,edema
4. Hypertension,weight loss,proteinuria
Answer:3
Rationale:Nephrotic syndrome is an alteration in kidney function secondary to increased glomerular basement membrane permeability to plasma protein.It is characterized by massive proteinuria,hypoalbuminemia,and edema. While hematuria and hypertension may be present,they are not pronounced.Gross hematuria and hypertension are associated with glomerulonephritis.Bacteriuria and fever are associated with a urinary tract infection.Because of the edema,a weight gain,not a weight loss,would be seen.
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