Antidiuretic hormone (ADH) is important in maintaining homeostasis in mammals. ADH is released from the hypothalamus in response to high tissue osmolarity. In response to ADH, the collecting duct and distal tubule in the kidney become more permeable to water, which increases water reabsorption into the capillaries. The amount of hormone released is controlled by a negative feedback loop. Based on the model presented, which of the following statements expresses the proper relationship between osmolarity, ADH release, and urine production?
(A) As tissue osmolarity rises, more ADH is released, causing less water to be excreted as urine.
(B) As tissue osmolarity rises, less ADH is released, causing less water to be excreted as urine.
(C) As tissue osmolarity rises, more ADH is released, causing more water to be excreted as urine.
(D) As tissue osmolarity rises, less ADH is released, causing more water to be excreted as urine.
Answer: (A) As tissue osmolarity rises, more ADH is released, causing less water to be excreted as urine.
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