The nurse is reviewing the mechanism of goiter development in a client with nontoxic multinodular goiters. Which statement best describes this process?
A) Thyroid enlargement occurs due to several growth factors, in addition to thyroid stimulating hormone (TSH), that cause some thyroid follicles to proliferate more than others.
B) Overall thyroid enlargement occurs without associated hypo- or hyperthyroidism, and is not induced by cysts, inflammation, or neoplasia.
C) Iodine deficiency causes some thyroid follicles to grow more quickly than to others, resulting in nodular changes and sequelae.
D) TSH receptor antibodies (TRAb) stimulate the TSH receptor to cause thyroid growth, goiter formation, and excessive secretion of thyroid hormones.
A) Thyroid enlargement occurs due to several growth factors, in addition to thyroid stimulating hormone (TSH), that cause some thyroid follicles to proliferate more than others.
Explanation: A) Nontoxic multinodular goiters develop when thyroid enlargement occurs due to several growth factors, in addition to thyroid stimulating hormone (TSH), that cause some thyroid follicles to proliferate more than others. Overall thyroid enlargement occurring without associated hypo- or hyperthyroidism, not induced by cysts, inflammation, or neoplasia describes nontoxic diffuse goiters. Endemic goiters occur when iodine deficiency causes some thyroid follicles to grow more quickly than to others, resulting in nodular changes and sequelae. Graves disease occurs when TSH receptor antibodies (TRAb) stimulate the TSH receptor to cause thyroid growth, goiter formation, and excessive secretion of thyroid hormones.
B) Nontoxic multinodular goiters develop when thyroid enlargement occurs due to several growth factors, in addition to thyroid stimulating hormone (TSH), that cause some thyroid follicles to proliferate more than others. Overall thyroid enlargement occurring without associated hypo- or hyperthyroidism, not induced by cysts, inflammation, or neoplasia describes nontoxic diffuse goiters. Endemic goiters occur when iodine deficiency causes some thyroid follicles to grow more quickly than to others, resulting in nodular changes and sequelae. Graves disease occurs when TSH receptor antibodies (TRAb) stimulate the TSH receptor to cause thyroid growth, goiter formation, and excessive secretion of thyroid hormones.
C) Nontoxic multinodular goiters develop when thyroid enlargement occurs due to several growth factors, in addition to thyroid stimulating hormone (TSH), that cause some thyroid follicles to proliferate more than others. Overall thyroid enlargement occurring without associated hypo- or hyperthyroidism, not induced by cysts, inflammation, or neoplasia describes nontoxic diffuse goiters. Endemic goiters occur when iodine deficiency causes some thyroid follicles to grow more quickly than to others, resulting in nodular changes and sequelae. Graves disease occurs when TSH receptor antibodies (TRAb) stimulate the TSH receptor to cause thyroid growth, goiter formation, and excessive secretion of thyroid hormones.
D) Nontoxic multinodular goiters develop when thyroid enlargement occurs due to several growth factors, in addition to thyroid stimulating hormone (TSH), that cause some thyroid follicles to proliferate more than others. Overall thyroid enlargement occurring without associated hypo- or hyperthyroidism, not induced by cysts, inflammation, or neoplasia describes nontoxic diffuse goiters. Endemic goiters occur when iodine deficiency causes some thyroid follicles to grow more quickly than to others, resulting in nodular changes and sequelae. Graves disease occurs when TSH receptor antibodies (TRAb) stimulate the TSH receptor to cause thyroid growth, goiter formation, and excessive secretion of thyroid hormones.
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