Which of the following statements best captures the etiology of the acute response phase of extrinsic (atopic) asthma?
A)
IgG production is heightened as a consequence of exposure to an allergen.
B)
Airway remodeling results in airflow limitations.
C)
Epithelial injury and edema occur along with changes in mucociliary function.
D)
Chemical mediators are released from presensitized mast cells.
Ans:
D
Feedback:
The acute response phase of extrinsic asthma is characterized by the release of chemical mediators from mast cells that have been sensitized. Epithelial injury and edema, as well as airway remodeling, are not associated with the acute phase, and IgE, not IgG, is primarily involved in asthma.
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