The nurse is explaining the epigenetic transgenerational inheritance due to diethylstilbestrol (DES) to a patient whose mother took DES while pregnant with her. What statement indicates that the patient understands the inheritance of epigenetic-induced changes?

A) "My children won't be affected because I didn't take DES."
B) "I can pass on these changes to my children."
C) "Changes cannot be passed on to my grandchildren."
D) "DES changes are not inherited."


B) "I can pass on these changes to my children."

Explanation: A) Exposure of a pregnant woman to such an agent as DES can result in epigenetic-induced changes that may be passed on to successive generations (i.e., great grandchildren and beyond) whether or not they are exposed to DES.
B) Epigenetic transgenerational inheritance due to environmental exposures results in altered epigenetic information of the germ line that is passed on to subsequent generations without continued environmental exposures. Thus, exposure of a pregnant woman to such an agent as DES can result in epigenetic-induced changes that may be passed on to successive generations (i.e., great grandchildren and beyond) whether or not they are exposed to DES.
C) Exposure of a pregnant woman to such an agent as DES can result in epigenetic-induced changes that may be passed on to successive generations (i.e., great grandchildren and beyond) whether or not they are exposed to DES.
D) Epigenetic transgenerational inheritance due to environmental exposures results in altered epigenetic information of the germ line that is passed on to subsequent generations without continued environmental exposures.

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